Vernon G, Baranova A, Younossi ZM. Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults. Aliment Pharmacol Ther. 2011;34(3):274-85.
Younossi ZM, et al. Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes. Hepatology. 2016;64(1):73-84.
Wong VWS, et al. Pathogenesis and novel treatment options for non-alcoholic steatohepatitis. The Lancet. 2016;1:56-67.
Chalasani, MD et al. The Diagnosis and Management of Non-Alcoholic Fatty Liver Disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association. Hepatology 2012;55(6):2005-23.
Laffitte et al. Combination Treatment of Tropifexor (LJN452) and Cenicriviroc Shows Additive Effects in a Diet-induced NASH Model. Poster 2052, presented at The Liver Meeting®, the American Association for the Study of Liver Diseases, Washington, DC, USA, October 20–24, 2017.
Safety, Tolerability, and Efficacy of a Combination Treatment of Tropifexor (LJN452) and Cenicriviroc (CVC) in Adult Patients With Nonalcoholic Steatohepatitis (NASH) and Liver Fibrosis (TANDEM). Available at: https://clinicaltrials.gov/ct2/show/NCT03517540. Last accessed October 2018.